Pancreatin micropellet cores suitable for enteric coating

A - Human Necessities – 61 – K

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A61K 9/36 (2006.01) A61K 38/46 (2006.01)

Patent

CA 2619477

Described herein are a process for manufacturing and using pancreatin micropellet cores and pancreatin micropellet cores obtainable according to that process which are substantially free of synthetic oils. Further described are enteric coated pancreatin mi¬ cropellets. In one embodiment, a pharmaceutical composition is provided comprising a pancreatin micropellet with an enteric coating being designed to deliver pancreatin to the upper portion of the intestine of a mammal for release.

L'invention porte sur un procédé de fabrication et d'utilisation de noyaux de microgranules de pancréatine et sur des noyaux de microgranules de pancréatine obtenus selon ledit procédé, et qui sont sensiblement exempts d'huiles synthétiques. L'invention décrit également des microgranules de pancréatine à enrobage entérique. Dans un mode de réalisation, l'invention porte sur une composition pharmaceutique renfermant un microgranule de pancréatine à enrobage entérique conçu pour libérer de la pancréatine dans la partie supérieure de l'intestin.

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