A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 31/4439 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2539982
Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a distintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.
L'invention concerne des multiparticules de sodium de pantoprazole qui évitent d'adhérer aux tubes nasogastriques et gastrotomiques. Les multiparticules de pantoprazole présentent un noyau sphéroïde de pantoprazole ou d'un énantiomère associé ou d'un sel correspondant, d'un agent de surface et d'un délitant, un sous-revêtement contenant de l'hydroxypropyl méthylcellulose (hypromellose) et de l'eau, un revêtement gastro-résistant sur le sous-revêtement, et un revêtement étanche final sur le revêtement gastro-résistant qui est composé d'hydroxypropyl méthylcellulose (hypromellose) et d'eau.
Fawzi Mahdi
Hasan Sumon A.
Nagi Arwinder
Saunders Richard William
Shah Syed M.
Torys Llp
Wyeth
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