C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/025 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) C07K 1/113 (2006.01) C07K 1/22 (2006.01) C07K 19/00 (2006.01) C12N 7/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2202090
Recombinant papilloma virus-like particles result from the expression of viral structural proteins L1 and/or L2 in which one or several sections of the L1 and/or L2 protein are deleted. The ability to form virus-like particles is at least the same as, preferably higher than, that of native reproduction and/or in vitro production processes.
L'invention concerne des particules de recombinaison semblables au virus du papillome, produites par expression des protéines structurales virales L1 et/ou L2 dans lesquelles une ou plusieurs sections de la protéine L1 et/ou L2 sont effacées. La capacité de reproduction de particules semblables à des virus est au moins égale, de préférence supérieure, à la capacité naturelle de reproduction et/ou à la productivité in vitro.
Gissmann Lutz
Heinrich Peter
Muller Martin
Paintsil Jeanette
Zhou Jian
Blake Cassels & Graydon Llp
Loyola University Of Chicago
Medigene Ag
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