Papilloma virus vaccine

Details Papilloma virus vaccine Papilloma virus vaccine

C - Chemistry, Metallurgy

12

N

C12N 15/866 (2006.01) A61K 39/12 (2006.01) C07K 14/025 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/37 (2006.01) C12P 21/02 (2006.01) C12N 15/64 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2113712

A method of providing papilloma virus like particles which may be used for diagnostic purposes or for incorporation in a vaccine for use in relation to infections caused by papilloma virus. The method includes an initial step of constructing one or more recombinant DNA molecules which each encode papilloma virus L1 protein or a combination of papilloma virus L1 pro-tein and papilloma virus L2 protein followed by a further step of transfecting a suitable host cell with one or more of the recombinant DNA molecules so that virus like particles (VLPs) are produced within the cell after expression of the L1 or combination of L1 and L2 proteins. The VLPs are also claimed per se as well as vaccines incorporating the VLPs.

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