Papillomavirus vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/12 (2006.01) A61P 31/20 (2006.01) A61P 35/00 (2006.01) A61K 48/00 (2006.01) C07K 14/025 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2649392

The present invention relates to the use of a composition comprising one or more early polypeptide(s) of human papillomavirus (HPV)-16 or a nucleic acid encoding one or more early polypeptide(s) of HPV-16 for the manufacture of a medicament for preventing or treating an infection or a pathological condition caused by at least one papillomavirus other than HPV-16. The invention is of very special interest in immunotherapy, in particular in preventing or treating HPV persistent infections possibly leading to cervical intraepithelial neoplasia (CIN) and ultimately to cervical cancer.

La présente invention concerne l'utilisation d'une composition comprenant un ou plusieurs polypeptides précoces de papillomavirus humain (HPV)-16 ou un acide nucléique codant pour un ou plusieurs polypeptides précoces de HPV-16 pour la production d'un médicament pour prévenir ou traiter une infection ou une pathologie causée par au moins un papillomavirus autre que HPV-16. L'invention présente un intérêt très spécial en immunothérapie, en particulier pour prévenir ou traiter des infections par HPV persistantes menant éventuellement à une néoplasie intra-cervicale (NIC) et enfin à un cancer cervical.

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