Para-amine substituted phenylamide glucokinase activators

Details Para-amine substituted phenylamide glucokinase activators Para-amine substituted phenylamide glucokinase activators

C - Chemistry, Metallurgy

07

D

C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4436 (2006.01) A61P 3/10 (2006.01) C07D 213/82 (2006.01) C07D 277/56 (2006.01) C07D 333/24 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2407763

Para-alkyl, aryl, cycloheteroalkyl or heteroaryl [carbonyl or sulfonyl] amino substituted phenyl amides active as glucokinase activators to increase insulin secretion which makes them useful for treating type II diabetes.

La présente invention concerne des phénylamides substitués para-alkyle, aryle, cyclohétéroalkyle ou hétéroaryle [carbonyle ou sulfonyle] amino, actifs en tant qu'activateurs de glucokinase, permettant d'augmenter la sécrétion d'insuline, ce qui les rend utiles pour traiter le diabète de type II.

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