Paracellular drug delivery system

Details Paracellular drug delivery system Paracellular drug delivery system

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 9/70 (2006.01) A61M 37/00 (2006.01) C07K 14/705 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2379661

The present invention provides a paracellular drug delivery system, related to Claudin-6. In another aspect of the present invention there is provided a composition comprising the Claudin-6-derived, specific peptides and peptide analogs to be generated or delivered for use within this system; the peptides may be conjugated to a drug to be used in targeted paracellular drug delivery. In another aspect of the present invention there is provided transgenic animals, wherein uses include, but are not limited to, models for studying human disease, paracellular drug delivery and tight junction permeability barrier biology in vivo.

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