Parallel identification of antibacterial targets and inhibitors

Details Parallel identification of antibacterial targets and inhibitors Parallel identification of antibacterial targets and inhibitors

C - Chemistry, Metallurgy

40

B

C40B 40/02 (2006.01) C12Q 1/18 (2006.01) C40B 40/04 (2006.01)

Patent

CA 2597633

The invention relates to methods for the parallel identification of compounds that have antibacterial activity as well as the target gene for that compound. This approach allows for coupled target validation/drug discovery, elucidation of mechanism(s) of antibacterial agents as well as discovery of new antibacterial pharmacophores having the same mechanism of action as existing agents.

Cette invention concerne des procédés d'identification en parallèle de composants ayant une activité antibactérienne ainsi que le gène cible de ce composant. Cette approche permet d'associer découverte de médicament/validation de la cible, de clarifier des mécanismes d'agents antibactériens et de découvrir de nouveaux pharmacophores antibactériens présentant le même mécanisme d'action que des agents existants.

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