Paramagnetic nanoparticles

A - Human Necessities – 61 – K

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A61K 49/18 (2006.01)

Patent

CA 2439381

The present invention relates to the preparation and use of nanoparticles, in particular paramagnetic nanoparticles, and their use as contrast enhancers for NMR-based methods of examination. A significant increase in contrast (e.g. from 100 to 200%) takes place according to the invention. An aqueous or organic synthesis leads to small nanoparticles which have a narrow size distribution and can also be advantageously used for many other industrial applications.

La présente invention concerne la production et l'utilisation de nanoparticules, en particulier de nanoparticules paramagnétiques et leur utilisation en tant qu'amplificateurs de contraste dans des méthodes d'analyse par résonance magnétique nucléaire. Selon cette invention, une amplification de contraste significative se produit (p. ex. 100 à 200 %). Des synthèses aqueuses ou organiques conduisent à de petites nanoparticules à répartition dimensionnelle étroite, pouvant être utilisées dans plusieurs autres applications techniques.

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