Parasiticidal pyrazoles

Details Parasiticidal pyrazoles Parasiticidal pyrazoles

C - Chemistry, Metallurgy

07

D

C07D 231/12 (2006.01) A01N 43/56 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07D 231/14 (2006.01) C07D 231/16 (2006.01) C07D 231/38 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2260412

Compounds of formula (I): (see fig I) or pharmaceutically, veterinarily or agriculturally acceptable salts thereof, or pharmaceutically, veterinarily or agriculturally acceptable solvates of either entity, wherein R1 is 2,4,6-trisubstituted phenyl or 3,5-disubstituted pyridin- 2-yl; R3 is hydrogen; C2 to C5 alkyl substituted with one or more halo and with hydroxy; C2 to C5 alkanoyl substituted with one or more halo; C2 to C6 alkenyl optionally substituted with one or more halo; halo; amino or CONH2; R5 is hydrogen, amino or halo; R2 and R4 are each independently selected from hydrogen, fluoro, chloro and bromo; R6 and R8 are hydrogen; and R7 is hydrogen or C1 to C4 alkyl optionally substituted with one or more halo; are parasiticidal agents.

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