Parathyroid hormone antagonists

Details Parathyroid hormone antagonists Parathyroid hormone antagonists

C - Chemistry, Metallurgy

07

K

530/7.1, 167/103

C07K 14/635 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1321282

7594P/5520P 17714IA TITLE OF THE INVENTION PARATHYROID HORMONE ANTAGONISTS ABSTRACT OF THE INVENTION The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone. The structure of the peptide hormone analogues is exemplified by parathyroid hormone wherein Glyl2 is substituted by D-Trp, L-Trp, L- or D- alpha- or beta- naphthylalanine, or D- or L- alpha-MeTrp.

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