Parathyroid hormone-containing emulsion for nasal...

Details Parathyroid hormone-containing emulsion for nasal... Parathyroid hormone-containing emulsion for nasal...

A - Human Necessities

61

K

A61K 47/22 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/72 (2006.01) A61K 38/29 (2006.01) A61K 47/26 (2006.01) A61K 47/28 (2006.01)

Patent

CA 2118655

A parathyroid hormone-containing emulsion for nasal administration, comprising parathyroid hormone as the active ingredient, at least, azacycloalkane derivative of the general formula [1]: (see fig 1) [1] wherein R is alkyl, m is an integer of 2-4, and n is an integer of 1-15, provided that R is alkyl of C5-11 in case where n is 1-3, as the absorption promotor, glycyrrhizic acid or its non-toxic salt, and a suitable amount of water.

mulsion contenant une hormone parathyroïdienne pour administration nasale, comportant une hormone parathyroïdienne comme matière active et au moins un dérivé azacycloalcane de la formule générale [1]: (voir la fig. 1) [1] où R est un groupe alkyle, m est un entier compris entre 2 et 4 et n est un entier compris entre 1 et 15, à la condition que R soit un groupe alkyle de type C5-11 si n est compris entre 1 et 3 et, comme adjuvant d'absorption, de l'acide glycyrrhizique ou son sel non toxique, et une quantité d'eau appropriée.

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