Parathyroid hypertensive factor

Details Parathyroid hypertensive factor Parathyroid hypertensive factor

C - Chemistry, Metallurgy

07

K

167/104, 167/147

C07K 14/635 (2006.01) A61K 31/275 (2006.01) A61K 31/44 (2006.01) A61K 31/55 (2006.01) A61K 35/55 (2006.01) A61K 39/395 (2006.01) C07K 1/36 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2030516

A new circulating factor from the parathyroid gland of some hypertensive mammals has been isolated and characterized. Polyclonal and monoclonal antibodies raised against this factor are usable as a screen for the presence of the factor. The factor is involved in the control of calcium uptake in cells. Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.

On a isolé et caractérisé un nouveau facteur de circulation provenant de la glande parathyroïde de certains mammifères hypertendus. On peut utiliser des anticorps polyclonaux et monoclonaux développés contre ce facteur, comme cribles déterminant la présence desdits facteurs. Ledit facteur joue un rôle dans la régulation de la fixation du calcium dans les cellules. On peut traiter des mammifères hypertendus afin d'abaisser la pression sanguine moyenne, par administration d'un agent bloquant les canaux calciques, avec un supplément de calcium et/ou de la vitamine D. L'effet hypotensif de cette combinaison est synergique, et la réaction à une dose est plus prévisible que l'administration de n'importe lequel de ces agents individuellement.

Affiliated with

Also associated with

Rating

Parathyroid hypertensive factor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Parathyroid hypertensive factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Parathyroid hypertensive factor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1889072