Parenteral chlorambucil for treatment of malignant and...

A - Human Necessities – 61 – K

Patent

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A61K 47/10 (2006.01) A61K 9/107 (2006.01) A61K 31/195 (2006.01) A61K 47/24 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2464475

A parenteral composition including a first solvent, made of an alcohol and a lipid, and a water soluble agent such as chlorambucil dissolved in the first solvent. The composition may be further diluted with an infusion fluid, such as normal saline, before infusion into a patient. The chlorambucil composition is useful for the treatment and suppression of malignant and autoimmune diseases.

L'invention concerne une composition parentérale contenant un premier solvant, constitué d'un alcool et d'un lipide, et un agent soluble dans l'eau, tel qu'un chlorambucil, dissous dans le premier solvant. La composition selon l'invention peut également être diluée avec un liquide de perfusion, tel qu'une solution saline normale, avant d'être perfusée à un patient. Cette composition de chlorambucil est utile dans le traitement et la suppression de maladies malignes et auto-immunes.

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