Parenterally administrable, heat sterilisable o/w emulsions...

Details Parenterally administrable, heat sterilisable o/w emulsions... Parenterally administrable, heat sterilisable o/w emulsions...

A - Human Necessities

61

K

A61K 49/04 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2101430

2101430 9218168 PCTABS00016 The invention relates to a parenterally administrable, heat-sterilisable O/W emulsion of an X-ray contrast agent with an inner phase of one or more suitable oil-soluble organic iodine compounds, especially iodised fatty acid esters, one or more emulsifiers and, where appropriate, co-emulsifiers and an outer phase of distilled water with isotonising additives, characterised by a content of a physiologically acceptable buffer of caustic soda and one or more suitable inorganic and/or organic phosphates. The emulsions obtained are distinguished by good shelf life and heat stability and can therefore be sterilised in autoclaves at 121·C.

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