Parenterally administrable microparticles

Details Parenterally administrable microparticles Parenterally administrable microparticles

A - Human Necessities

61

K

A61K 9/50 (2006.01)

Patent

CA 2429100

A process for producing microparticles containing biologically active substance, in which process an aqueous solution of the said substance is prepared, this solution is mixed with an aqueous soltion of PEG such that the substance is concentrated and/or solidified, the substance is optionally washed, the substance is mixed with an aqueous starch solution, the composition obtained is mixed, after the admixture of the starch solution, with a polymer soltution, thereby forming an emulsion of starch droplets in the polymer solution, the starch droplets are solidified into microparticles, the droplets are solidified into microparticles, the microparticles are dried and a release-controlling shell is optionally applied to these. Novel microparticles which are obtainable by means of this process.

L'invention concerne un procédé permettant de produire des microparticules contenant une substance active au niveau biologique. Ce procédé consiste à préparer une solution aqueuse de ladite substance, à mélanger cette solution avec une solution aqueuse de PEG telle que la substance est concentrée et/ou solidifiée, à nettoyer éventuellement la substance, à mélanger la substance avec une solution d'amidon aqueuse, à mélanger la composition obtenue, après addition de la solution d'amidon, avec une solution polymère, de manière à former une émulsion de gouttelettes d'amidon dans la solution polymère, les gouttelettes d'amidon étant solidifiées dans des microparticules, à sécher les microparticules et appliquer éventuellement une coquille de régulation d'administration à ses microparticules. L'invention concerne également les nouvelles microparticules pouvant être obtenues à l'aide de ce procédé.

Affiliated with

Also associated with

Rating

Parenterally administrable microparticles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Parenterally administrable microparticles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Parenterally administrable microparticles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1633624