A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/4525 (2006.01)
Patent
CA 2277480
Paroxetine hydrochloride is obtained in a free-flowing and easily soluble form (suitable for preparing solid formulations or aqueous solutions, suitable for parenteral use) by spray-drying solutions of paroxetine hydrochloride hemihydrate or other anhydrate/hydrate/solvate/amorphous forms.
La présente invention concerne un chlorhydrate de paroxétine obtenu sous forme soluble à écoulement fluide (convenant à la préparation de formulations solides ou de solutions aqueuses et à des utilisations parentérales). On procède pour cela par séchage par pulvérisation des solutions semi-hydratées de chlorhydrate de paroxétine ou d'autres formes amorphes, déshydratées, hydratées, ou solvatées.
Jacewicz Victor Witold
Ward Neal
Gowling Lafleur Henderson Llp
Smithkline Beecham P.l.c.
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