Parthenolide free bioactive ingredients from feverfew...

A - Human Necessities – 01 – N

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A01N 65/00 (2006.01)

Patent

CA 2643255

The present invention relates to bioactive ingredients that include isolated bioactive fractions derived from cell juice of fresh biomass of a feverfew (Tanacetum partheniuni) plant. The bioactive fractions are either free of or substantially free of .alpha.-unsaturated .gamma.-lactones (e.g., parthenolide). Further, the bioactive fractions have anti-inflammatory and antioxidant activity. The present invention also relates to a method for isolating a bioactive fraction that is derived from cell juice of fresh biomass of a feverfew (Tanacetum partheniuni) plant and that is at least substantially free of .alpha.-unsaturated .gamma.-lactones (e.g., parthenolide). The present invention also relates to a method for preparing a stabilized cell juice serum fraction and a stabilized concentrated cell juice serum fraction that are free of .alpha.-unsaturated .gamma.-lactones (e.g., parthenolide). The present invention also relates to a bioactive composition that includes a mixture of one or more of the isolated bioactive fractions of the present invention.

La présente invention concerne des ingrédients bioactifs qui comprennent des fractions bioactives isolées dérivées du jus de cellules de la biomasse fraîche d'une plante de grande camomille (Tanacetum parthenium). Les fractions bioactives sont soit exemptes soit sensiblement exemptes de g-lactones a-insaturées (par exemple de parthénolide). En outre, les fractions bioactives ont une activité anti-inflammatoire et antioxydante. La présente invention concerne également un procédé servant à isoler une fraction bioactive qui est dérivée du jus de cellules de la biomasse fraîche d'une plante de grande camomille (Tanacetum parthenium) et qui est au moins sensiblement exempte de g-lactones a-insaturées (par exemple de parthénolide). La présente invention concerne également un procédé servant à préparer une fraction stabilisée de sérum de jus de cellules et une fraction concentrée stabilisée de sérum de jus de cellules qui sont exemptes de g-lactones a-insaturées (par exemple de parthénolide). La présente invention concerne également une composition bioactive qui comprend un mélange d'une ou plusieurs des fractions bioactives isolées de la présente invention.

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