A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/30 (2006.01) A61L 27/58 (2006.01) C12M 3/00 (2006.01) C12N 5/00 (2006.01)
Patent
CA 2687637
The present invention is directed to a scaffold for tissue engineering, comprising a support structure having an outer surface, at least a part of the outer surface being covered by a bioactive material layer that allows cell attachment, wherein the bioactive material layer is at least partially degradable in an environment of use, to allow a detachment of the cells from the support structure by degradation of the bioactive material layer. The invention is further directed to the use of an at least partially degradable bioactive material layer on a scaffold for tissue engineering, for allowing detachment of the cells or grown tissue by degradation of the bioactive material layer.
L'invention concerne un échafaudage pour ingéniérie tissulaire qui comprend une structure de support comportant une surface extérieure dont une partie au moins est recouverte d'une couche de matériau bioactif permettant la fixation cellulaire, la couche de matériau cellulaire étant au moins partiellement biodégradable dans un environnement d'utilisation afin de permettre que les cellules se détachent de la structure de support lorsque la couche de matériau biodégradable se dégrade. L'invention se rapporte en outre à l'utilisation d'au moins une couche de matériau bioactif partiellement dégradable sur un échafaudage en ingéniérie tissulaire, destinée à permettre que les cellules ou le tissu obtenu par croissance se détachent lorsque la couche de matériau cellulaire bioactif se dégrade.
Borden Ladner Gervais Llp
Cinvention Ag
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