Partially purified bone-inducing factor

Details Partially purified bone-inducing factor Partially purified bone-inducing factor

A - Human Necessities

61

K

167/104, 167/327

A61K 35/32 (2006.01)

Patent

CA 1266435

PARTIALLY PURIFIED BONE-INDUCING FACTOR Abstract A partially purified protainaceous bone- inducing factor of 10,000 to 30,000 daltons is described. It is derived from demineralized bovine bone by extraction with a chaotropic agent, gel filtration, cation exchange chromatography using carboxymethyl cellulose at pH 4.8 and gradient elution with NaCl at 10 mM to about 150 mM.

507485

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