Particle based vaccine composition

Details Particle based vaccine composition Particle based vaccine composition

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 39/02 (2006.01) A61K 39/39 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2366613

A pharmaceutical composition which comprises microparticles comprising (i) a biologically active compound capable of generating an immune response in an animal to which it is administered which is protective against a pathogen; (ii) a polymeric material capable of forming microspheres; and (iii) an immunostimulant comprising a phospholipid. The composition is particularly useful for the oral administration of vaccines.

L'invention concerne une composition pharmaceutique qui comporte des microparticules contenant (i) un composé biologiquement actif qui est capable de générer une réponse immunitaire chez un animal auquel on l'a administré, et qui assure la protection contre un agent pathogène; (ii) une matière polymère susceptible de former des microsphères et (iii) un immunostimulant comportant un phospholipide. Cette composition s'avère particulièrement utile pour l'administration orale de vaccins.

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