Particle formation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/00 (2006.01) B01J 2/02 (2006.01) B01J 2/04 (2006.01)

Patent

CA 2665349

A process for producing particles of a substance is described wherein a solution of the substance in a solvent is delivered in at least one shot into a supercritical fluid. The supercritical fluid is a non-solvent for the substance and is miscible with the solvent. Particles of the substance distributed in a mixture of the solvent and the supercritical fluid are formed.

La présente invention concerne un procédé de production de particules d'une substance, dans lequel une solution de la substance dans un solvant est administrée sous la forme d'au moins un jet dans un fluide supercritique. Le fluide supercritique est un non-solvant pour la substance et est miscible dans le solvant. Des particules de la substance distribuées dans un mélange du solvant et du fluide supercritique sont formées.

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