Particle-forming compositions containing fused...

Details Particle-forming compositions containing fused... Particle-forming compositions containing fused...

C - Chemistry, Metallurgy

07

D

C07D 498/22 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2545545

A non-aqueous, particle-forming, fused pyrrolocarbazole-containing composition is disclosed. Upon contact with an aqueous medium, the particle-forming composition spontaneously disperses into suspended particles, thereby forming a stable suspension that provides greatly improved bioavailability of orally administered fused pyrrolocarbazole compounds.

L'invention concerne une composition non aqueuse contenant des pyrrolocarbazoles fusionnés, , pour une formation de particules. Lors d'un contact avec un milieu aqueux, la composition de formation de particules se disperse spontanément en particules en suspension, ce qui permet de former une suspension stable permettant d'obtenir une biodisponibilité grandement améliorée de composés pyrrolocarbazoles fusionnés oralement administrés.

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