C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/61 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2098599
2098599 9308292 PCTABS00021 A method is disclosed for the convenient transformation of the somatic cells of animals to introduce therapeutic proteins into the animal. Somatic cell transformation is useful for medical and veterinary care of genetic diseases, and other therapeutic or animal improvement purposes. Copies of an exogenous genetic construction can be coated on carrier particle and accelerated into the interior of cells of the animal in situ. If the exogenous genetic construct includes a secretory signal peptide, it has been found that circulating levels of the protein can be achieved by simple transdermal insertion of the carrier particles
Cheng Liang
Martinell Brian F.
Mccabe Dennis E.
Swain William F.
Yang Ning-Sun
Agracetus Inc.
Borden Ladner Gervais Llp
Cheng Liang
Martinell Brian F.
Mccabe Dennis E.
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