Particles comprising amphiphilic copolymers, having a...

A - Human Necessities – 61 – K

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Details

A61K 31/74 (2006.01) A61K 9/51 (2006.01) C08F 8/00 (2006.01) C08J 3/24 (2006.01)

Patent

CA 2258744

Provided are methods of inhibiting bile acid uptake from the gastrointestinal system and reducing blood serum cholesterol by administering to a mammal, such as a human, an effective amount of particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain.

La présente invention fournit des méthodes d'inhibition des remontées d'acide biliaire du système gastro-intestinal et permet de réduire le cholestérol de sérum du sang en administrant à un mammifère, tel qu'un humain, une quantité efficace de particules comprenant des copolymères amphiphiles, possédant un domaine de réticulation croisée et un domaine de noyau interne.

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