Particles comprising drospirenone encapsulated in a polymer

A - Human Necessities – 61 – K

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Details

A61K 9/16 (2006.01) A61K 9/00 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2759667

The present invention relates to particles comprising Drospirenone encapsulated in a polymer selected from the group consisting of glycolic acid polymer, lactic acid polymer, poly caprolactones, poly anhydrides and any copolymer of these, e.g., poly(lactic acid-co-glycolic acid) polymer and any combination of these. Furthermore, the present invention also relates to compositions comprising such particles. The present invention also relates to the use of such particles or compositions as contra-ceptives and for treatment of diseases, disorders and symptoms associated with deficient endogenous levels of estrogen in women.

L'invention concerne des particules comprenant de la drospirénone encapsulée dans un polymère choisi dans le groupe comprenant polymère d'acide glycolique, polymère d'acide lactique, poly-caprolactones, poly-anhydrides et un quelconque copolymère de ceux-ci, par exemple polymère poly(acide lactique-acide co-glycolique) et une quelconque combinaison de ceux-ci. L'invention concerne en outre des compositions comprenant de telles particules. L'invention concerne également l'utilisation de ces particules ou compositions comme contraceptifs et pour le traitement de maladies, troubles et symptômes associés à des niveaux endogènes déficients d'oestrogènes chez la femme.

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