Particles for the delivery of active agents

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01)

Patent

CA 2565236

Particles of less than 100 microns, where an active agent is coated with a matrix of cationic and anionic polymers, are efficient vehicles for delivering active agents to tissues such as skin and mucosal membranes. Such particles are able to deliver compounds to skin with little associated irritation. Prior art topical formulations typically have the disadvantage of causing significant skin irritation.

Des particules de moins de 100 microns, dans lesquelles un agent actif est revêtu d'une matrice de polymères cationiques et anioniques, sont des véhicules efficaces pour libérer des agents actifs sur des tissus comme la peau et les muqueuses. Lesdites particules peuvent libérer des composés sur la peau avec peu d'irritation associée. Les formulations topiques de l'état antérieur de la technique présentent généralement le désavantage de causer d'importantes irritations de la peau.

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