Particles suitable for tabletting into diagnostic reagents

Details Particles suitable for tabletting into diagnostic reagents Particles suitable for tabletting into diagnostic reagents

G - Physics

01

N

150/1, 167/37

G01N 33/50 (2006.01) C12Q 1/00 (2006.01) G01N 33/531 (2006.01) G01N 33/548 (2006.01)

Patent

CA 1303490

"PARTICLES SUITABLE FOR TABLETTING INTO DIAGNOSTIC REAGENTS" Abstract of the Disclosure A completely water-soluble, solid, labile biochemical-containing diagnostic reagent is prepared without the need of a lyophilization step, by spraying, preferably by a fluidized bed process, an aqueous solution of labile biochemical, e.g., an enzyme, onto small parti- cles, e.g., lower than 20 mesh, of an inert, completely water-soluble solid bulking agent, e.g., mannitol; drying the resultant labile biochemical-coated bulking agent to the desired dryness; and then forming resultant dried labile biochemical-coated bulking agent into a tablet suitable for a diagnostic test reagent, said tablet having a predetermined rate of dissolution.

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