Particles which are surface coated with hyaluronan or one of...

A - Human Necessities – 61 – K

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Details

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/51 (2006.01)

Patent

CA 2493470

The invention relates to particles comprising a core based on at least one biodegradable organo-soluble polymer. The inventive particles are characterised in that at least part of the surface thereof is coated with at least one hyaluronan or one of the derivatives thereof, said hyaluronan being a water-soluble, amphiphilic hyaluronan of which the carboxylic functions are in part transformed in order to form hydrophobic groups.

« Particules revêtues en surface de hyaluronane ou d'un de ses dérivés et leur utilisation á titre de vecteurs biologiques pour des matières actives » La présente invention concerne des particules dont le c.oelig.ur est á base d'au moins un polymère organosoluble biodégradable, caractérisées en ce qu'elles sont revêtues, au moins partiellement en surface d'au moins un hyaluronane ou de l'un de ses dérivés, ledit hyaluronane étant un hyaluronane amphiphile, hydrosoluble et dont les fonctions carboxyliques sont en partie transformées pour figurer des groupes hydrophobes.

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