Particles with improved solubilization capacity

Details Particles with improved solubilization capacity Particles with improved solubilization capacity

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/127 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2451432

A particle is disclosed that comprises a first volume of hydrophobe-rich material with tunable dissolution and solubilization characteristics and a distinct second volume of nanostructural nonlamellar liquid crystalline material, said second volume containing said first domain and being capable of being in equilibrium with said first volume. Preferably, the nanostructured nonlamellar liquid crystalline material is capable of being in equilibrium with a polar solvent or a water-immiscible solvent or both.

L'invention concerne une particule caractérisée en ce qu'elle comprend un premier volume d'un matériau à caractère hydrophobe prononcé, ayant des caractéristiques de dissolution et de solubilisation pouvant être adaptées, et un second volume distinct d'un matériau cristallin liquide non lamellaire nanostructuré, en ce que ledit second volume contient le premier domaine et est capable d'être en équilibre avec ledit premier volume. De préférence, le matériau cristallin liquide non lamellaire nanostructuré est capable d'être en équilibre avec un solvant polaire ou avec un solvant non miscible à l'eau, ou avec les deux.

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