A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/26 (2006.01) A23L 1/30 (2006.01) A61K 31/375 (2006.01) C07H 17/04 (2006.01) C12P 19/60 (2006.01) A61K 9/14 (2006.01)
Patent
CA 2714377
The present invention aims to provide a particulate composition containing anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic acid having a significantly, hardly solidifiable property compared to conventional ones in a grade for use in quasi-drugs; a process for producing the same; and uses thereof. The present invention solves the above object by providing a particulate composition containing anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic in an amount of over 98.0% by weight but less than 99.9% by weight, on a dry solid basis; or a degree of crystallinity of 90% or higher for anhydrous crystalline 2-O- .alpha. -D-glucosyl-L-ascorbic acid, when calculated based on a profile of powder X-ray diffraction analysis of the particulate composition, and a dynamic vapor sorption level of 0.01% by weight or lower, when kept at 25°C under a relative humidity of 35% by weight for 12 hours after removal water in the particulate composition under nitrogen gas stream; and by providing a process for producing the same and uses thereof.
Fukuda Shigeharu
Izawa Seisuke
Miyake Toshio
Nishimoto Tomoyuki
Shibuya Takashi
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Macrae & Co.
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