Particulate lipid pharmaceutical composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/44 (2006.01) A61K 9/107 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 47/04 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2620299

A particulate lipid pharmaceutical composition comprises a particulate solid non-lipid carrier and an oil-in-water emulsion on the carrier. The emulsion comprises a dissolved or dispersed pharmacologically active agent. The oil-in- water emulsion is released from the carrier on contact with an aqueous media to form an oil-in-water emulsion in the media. Also disclosed is a method of producing the composition and a tablet containing it; sachets and capsules filled with the composition; use of the composition and the tablet as a medicine; a method of administering the composition to a patient.

Préparation pharmaceutique lipidique particulaire comprenant un vecteur solide particulaire non lipidique et une émulsion huile dans l'eau sur le vecteur. L'émulsion comprend un principe pharmacologiquement actif dissous ou dispersé. L'émulsion huile dans l'eau est libérée par le vecteur au contact d'un milieu aqueux pour former une émulsion huile dans l'eau dans le milieu. La présente invention concerne également une méthode de production de la préparation et d~un comprimé la contenant ; des sachets et des gélules remplis de la préparation ; l'emploi de la préparation et du comprimé comme médicament ; une méthode d'administration de la préparation à un patient.

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