Particulate material for use in the analysis of liquid samples

G - Physics – 01 – N

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167/37, 150/7

G01N 33/48 (2006.01) G01N 27/74 (2006.01)

Patent

CA 1080123

ABSTRACT OF THE DISCLOSURE A particulate material suitable for automatic assay of fluid samples, particularly immunossays, in which a reaction product of the assay is bound to the material and separated from the reaction mixture by use of a magnetic trap. The particulate material comprises a reagent and one or more magnetic particles in a matrix of binding material and has a controlled specific gravity approaching that of the fluid sample so as to retard separation of the particulate material when mixed with the fluid sample. The binding material is selected from a group consisting of cellulose or a cellulose derivative, a polymer or synthetic polymeric material, and agarose. The material is of especial use in radioimmunoassays carried out in an automated continuous-flow manner.

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