Particulate vector and pharmaceutical composition containing...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2161121

The invention relates to a particulate vector, characterized in that it comprises, from the inside to the outside, a non-liquid hydrophilic core, an external layer comprised of lipid compounds grafted on the core by covalent bonds. The invention also relates to a pharmaceutical composition containing such vectors, as well as to a process for enhancing the activity of the polypeptide cellular mediator.

L'invention concerne un vecteur particulaire, caractérisé en ce qu'il comporte, de l'intérieur vers l'extérieur, un noyau hydrophile non liquide, une couche externe constituée de composés lipidiques, greffés sur le noyan par des liaisons covalentes. Elle concerne également une composition pharmaceutique contenant de tels vecteurs, ainsi qu'un procédé d'amplification de l'activité d'un médiateur cellulaire polypeptidique.

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