Particulates of a crth2 antagonist

Details Particulates of a crth2 antagonist Particulates of a crth2 antagonist

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/33 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2690172

Provided herein are particulates of {4,6-bis(dimethylamino)-2-(4-(4- (trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl} acetic acid in amorphous or crystalline forms, processes for their preparation, pharmaceutical compositions comprising them, and methods of their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease.

L'invention porte sur des particules d'acide {4,6-bis(diméthylamino)-2-(4-(4-(trifluorométhyl)benzamido)benzyl)pyrimidin-5-yl} acétique dans des formes amorphes ou cristallines, sur des procédés permettant de les préparer, sur des compositions pharmaceutiques les comprenant, et sur des procédés pour les utiliser pour le traitement, la prévention ou l'amélioration d'un ou plusieurs symptômes d'un trouble ou d'une maladie à médiation par CRTH2.

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