A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01)
Patent
CA 2735634
Provided is a patch preparation containing: a support; and an adhesive layer containing a drug on the surface of the support, wherein a crystal of the drug is formed in the adhesive layer immediately after application of a physical stimulation to the adhesive layer, while a crystal of the drug is formed during preservation after the physical stimulation. According to the present invention, a patch preparation which does not require increase in the area and thickness of an adhesive layer, achieves sufficiently high skin permeation amount of a drug, shows good adhesiveness to the skin and permits a long-term adhesion, and a production method thereof can be provided.
Akemi Hitoshi
Hanatani Akinori
Iwao Yoshihiro
Matsuoka Kensuke
Okazaki Arimichi
Fetherstonhaugh & Co.
Nitto Denko Corporation
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