Pathogeniv tau mutations

Details Pathogeniv tau mutations Pathogeniv tau mutations

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2330944

Isolated nucleic acid molecules that include a tau gene sequence are described. The tau gene sequences have a mutation linked to a Tau pathology. Transgenic non-human mammals containing a Tau pathology are also described.

L'invention porte sur des molécules d'acide nucléique isolées qui comprennent une séquence du gène tau. Les séquences du gène tau ont une mutation liée à une pathologie Tau. L'invention porte également sur des mammifères transgéniques présentant une pathologie Tau.

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