Patient-specific white blood cell malignancy vaccine from...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2318557

Membrane-proteoliposome structures (MPs) are useful in preparing patient- specific vaccines against specific white blood cell (WBC) malignancies. The inventive MPs typically contain a membrane component derived from a specific WBC. Other useful components include immunostimulators and exogenous lipids. The resulting vaccines are both patient- and malignancy-specific.

La présente invention concerne des structures de protéoliposomes à membrane utilisées dans la préparation de vaccins dirigés contre des tumeurs malignes de leucocytes spécifiques. Les protéoliposomes à membrane de l'invention contiennent un composant membranaire dérivé d'un leucocyte précis. D'autres composants utilisés comprennent les immunostimulants et les lipides exogènes. L'invention permet d'obtenir des vaccins à la fois spécifiques de patient et spécifiques de tumeur.

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