Pattern recognition method for diagnosis of systemic...

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G01N 33/564 (2006.01)

Patent

CA 2424764

An array of autoantibodies is quantitated in a patient sample and analyzed toward a diagnosis of systemic autoimmune diseases. The analysis uses any of various known pattern recognition techniques to compare the array of quantitation data to sets of data previously obtained from subjects having known systemic autoimmune diseases, thereby determining the particular disease(s) that the patient is suffering from as well as the degree of confidence or likelihood of accuracy of the determination. The method is effective in identifying a single disease and also in identifying two or more diseases simultaneously present. The method is readily susceptible to automated data processing, eliminating much of the human judgment and error that were previously entailed in diagnosing these diseases.

La présente invention concerne un ensemble d'autoanticorps qui est quantifié dans un échantillon d'un patient et est analysé en vue d'un diagnostic de maladies auto-immunes systémiques. L'analyse met en oeuvre une quelconque technique de reconnaissance de formes connue, afin de comparer l'ensemble de données de quantification à des ensembles de données obtenus précédemment à partir de sujets présentant des maladies auto-immunes systémiques connues, ce qui permet de déterminer la/les maladie(s) particulière(s) dont le patient souffre, ainsi que le niveau de confiance ou la probabilité de précision de cette détermination. Ce procédé est efficace aussi bien dans l'identification d'une maladie que dans l'identification de deux ou plusieurs maladies présentes en même temps. Ce procédé peut facilement être soumis à un traitement automatique des données, ce qui permet d'éliminer une majeure partie du jugement et de l'erreur humains qui étaient précédemment impliqués dans le diagnostic de ces maladies.

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