Pcp receptor ligands and the use thereof

Details Pcp receptor ligands and the use thereof Pcp receptor ligands and the use thereof

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/55 (2006.01) A61K 31/655 (2006.01) A61K 31/695 (2006.01) C07F 7/10 (2006.01) A61K 31/645 (1990.01) A61K 43/00 (1990.01)

Patent

CA 2109420

2109420 9219621 PCTABS00017 The invention relates to 5-(iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene and derivatives thereof. The invention also relates to the use of such compounds for the treatment or prevention of neuronal loss in ischemia, hypoxia, brain or spinal cord trauma, as well as for the treatment of Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome.

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