Pcv-2 vaccine

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 39/12 (2006.01) A61P 31/20 (2006.01)

Patent

CA 2620727

The present invention relates to a vaccine against porcine drcovirus type 2 (PCV-)2 and a method for the manufacture of such a vaccine, for protecting piglets against PCV-2 infection. It has been found that a vaccine comprising at least 20 microgram/dose of ORF-2 protein of porcine circovirus type 2 (PCV- 2 is capable of eliciting a protective immune response against PCV-2 (and thus against PMWS) even when they have a relatively high titer of MDA against PCV- 2. A vaccine according to the invention may contain a recombinant ORF-2 protein, wherein said recombinant protein is preferably produced by way of expression from a baculovirus expression vector in insect cells, said baculovirus expression vector containing the PCV-2 ORF-2 gene sequence under control of a suitable promoter.

La présente invention concerne un vaccin contre le circovirus porcin de type 2 (PCV-2) et un procédé pour la fabrication d'un tel vaccin, pour protéger des porcelets contre l'infection par PCV-2. Il a été découvert qu'un vaccin comprenant au moins 20 microgrammes/dose de protéine ORF-2 de circovirus porcin de type 2 (PCV-2) est capable de provoquer une réponse immunitaire protectrice contre PCV-2 (et donc contre PMWS) même lorsqu'ils ont un titre relativement élevé de MDA contre PCV-2. Un vaccin selon l'invention peut contenir une protéine ORF-2 recombinante, ladite protéine recombinante étant de préférence produite au moyen de l'expression dans un vecteur d'expression de baculovirus dans des cellules d'insecte, ledit vecteur d'expression de baculovirus contenant la séquence du gène ORF-2 de PCV-2 sous le contrôle d'un promoteur approprié.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Pcv-2 vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pcv-2 vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pcv-2 vaccine will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1663478

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.