Pde4 inhibitors for the treatment of neoplasms of lymphoid...

Details Pde4 inhibitors for the treatment of neoplasms of lymphoid... Pde4 inhibitors for the treatment of neoplasms of lymphoid...

A - Human Necessities

61

K

A61K 31/502 (2006.01) A61K 31/00 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2512819

The invention relates to the use of certain PDE4 inhibitors alone or in combination with one or more differentiation inducing agents and/or an agent effective in raising intracellular concentrations of cAMP or a stable analogue of cAMP in the preparation of pharmaceutical compositions for the treatment of neoplasms of lymphoid cells.

L'invention concerne l'utilisation de certains inhibiteurs de PDE4 seuls ou combinés à des agent à induction de différenciation et/ou un agent efficace dans l'augmentation des concentrations intracellulaires de cAMP ou un analogue stable de cAMP dans la préparation de compositions pharmaceutiques pour le traitement de néoplasmes de cellules lymphoïdes.

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