Peg-based macromonomers, chemically inert polymers prepared...

C - Chemistry – Metallurgy – 08 – G

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C08G 65/32 (2006.01) C07K 1/04 (2006.01) C08F 283/06 (2006.01) C08F 290/06 (2006.01) C08G 65/22 (2006.01) C08G 65/26 (2006.01)

Patent

CA 2345332

The present invention relates to macromonomers containing ethylene glycol repeat units, to chemically inert polymers prepared therefrom and to the use of such polymers in solid phase biochemical assays. A macromonomer of polyethylene glycol having repeat units in the range 6-300 and having at least one end terminated by an ether group having formula (I) where m is an integer of 0-10, a is an integer of 1-4, and R is H or alkyl or aryl or arylalkyl; or having formula (II) where m is an integer of 1-10, and R is H or alkyl or aryl or arylalkyl.

L'invention concerne des macromonomères contenant des motifs de répétition d'éthylène-glycol, des polymères inertes au plan chimique, préparés à partir desdits macromonomères, et l'utilisation desdits polymères dans des essais biochimiques en phase solide. Un macromonomère de polyéthylène-glycol possédant des motifs de répétition de l'ordre de 6-300 et possédant au moins une extrémité se terminant par un groupe éther de formule (I), dans laquelle m vaut un entier de 0-10, a un entier de 1-4, et R représentant H ou alkyle, aryle ou arylalkyle ; ou de formule (II) dans laquelle m vaut un entier de 0-10, et R représente H ou alkyle, aryle ou arylalkyle.

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