Peg-poly(ortho ester) graft copolymers and pharmaceutical...

Details Peg-poly(ortho ester) graft copolymers and pharmaceutical... Peg-poly(ortho ester) graft copolymers and pharmaceutical...

C - Chemistry, Metallurgy

08

G

C08G 65/34 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2601547

This invention relates to graft copolymer delivery vehicles comprising a polyethyleneglycol-poly(ortho ester), and to controlled release pharmaceutical compositions comprising the delivery vehicle and an active agent. The graft copolymer delivery vehicles may be thermogels graft copolymers. The pharmaceutical compositions may be in the form of a topical, syringable, or injectable formulation for local controlled delivery of the active agent.

La présente invention a trait à des excipients d'administration à base de copolymères greffés comportant un polyéthylèneglycol-poly(ortho-ester), et à des compositions pharmaceutiques à libération contrôlée comprenant l'excipient d'administration et un principe actif. Les excipients d'administration à base de copolymères greffés peuvent être des copolymères greffés de type thermogel. Les compositions pharmaceutiques peuvent se présenter sous la forme d'une formulation topique, d'administration par seringue, ou par injection pour la libération contrôlée du principe actif.

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