Peg-polyacetal diblock and triblock copolymers and...

A - Human Necessities – 61 – K

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A61K 47/00 (2006.01)

Patent

CA 2601546

This invention relates to block copolymer delivery vehicles comprising a polyethyleneglycol-polyacetal, and to controlled release pharmaceutical compositions comprising the delivery vehicle and an active agent. The block copolymers of the invention may be thermogel block copolymers. The pharmaceutical compositions may be in the form of a topical, syringable, or injectable formulation for local controlled delivery of the active agent.

L'invention concerne des véhicules d'administration de copolymère bloc comprenant un polyéthylèneglycol-polyacétal, et des compositions pharmaceutiques à libération contrôlée comprenant le véhicule d'administration et un principe actif. Les copolymères blocs de l'invention peuvent consister en des copolymères blocs thermogènes. Les compositions pharmaceutiques peuvent être sous forme de formulation topique, administrable par seringue, ou injectable pour une administration locale contrôlée du principe actif.

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