Pendant fatty acid imaging agents

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2482327

The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The compounds comprise a metal chelating agent bound to a radionuclide carbonyl ligand, which is pendantly bound to a fatty acid. The disclosure also provides for a method administering an imaging agent with a high specificity for the myocardium.

L'invention concerne des composés d'acides gras pendants à utiliser dans une imagerie diagnostique, (en particulier pour le système cardio-vasculaire), ainsi que des trousses comprenant ces composés. Ces composés comprennent un agent chélateur métallique lié à un ligand carbonyle radionucléide, relié à un acide gras par une liaison pendante. L'invention concerne également un procédé d'administration d'un agent d'imagerie présentant une haute spécificité pour le myocarde.

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