Penetration enhancement with binary system of cell envelope...

Details Penetration enhancement with binary system of cell envelope... Penetration enhancement with binary system of cell envelope...

A - Human Necessities

61

K

167/159

A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01)

Patent

CA 1339073

Penetration-enhancing pharmaceutical compositions for topical transepidermal and percutaneous application are disclosed. These compositions are made up of a safe and effective amount of an active pharmaceutical permeant contained in a novel penetration-enhancing vehicle comprising, (i) a cell-envelope disordering compound; and (ii) a lower alkanol selected from the group consisting of ethanol, propanol and isopropanol and mixtures thereof. The weight ratio of cell-envelope disordering compound to lower alkanol is between about 50:1 to 1:50 and preferably between about 9:1 and 1:9. Preferred cell-envelope disordering compounds are oleic acid, oleyl alcohol, glycerol oleates, methyl oleate, methyl laurate and mixtures thereof. The novel penetration enhancer vehicles are non-irritating to the skin and enhance the penetration of a broad spectrum of pharmaceutical permeants including hydrophilic salts.

561943

Affiliated with

Also associated with

Rating

Penetration enhancement with binary system of cell envelope... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Penetration enhancement with binary system of cell envelope..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Penetration enhancement with binary system of cell envelope... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1168921