C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/110
C07D 499/00 (2006.01) A61K 31/43 (2006.01) C07D 499/32 (2006.01) A61K 31/545 (2006.01)
Patent
CA 1119164
Abstract of the Disclosure Penicillanic acid l,l-dioxide, and esters thereof readily hydrolyzable in vivo, are useful as antibacterial agents, and also for enhancing the effectiveness of several .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria. Derivatives of penicillanic acid l,l-dioxide having the carboxy group protected by a conventional penicillin carboxy protecting group are useful intermediates to penicillanic acid l,l-dioxide. Penicillanic acid l-oxides and certain esters thereof are useful chemical intermediates to penicillanic acid l,l-dioxide and its esters.
304796
Limited Pfizer
Smart & Biggar
LandOfFree
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