Penicillins and their preparation

C - Chemistry – Metallurgy – 07 – D

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260/114.3

C07D 499/70 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1064911

ABSTRACT OF THE DISCLOSURE Penicillins of the formula Image wherein X is O or S; Y is H or alkyl; Z is Image or Image , R1 is H or OH; and R2 and R3 each are H or wherein X is O or S; Y is H or alkyl; R2 and R3 each are H or taken together with the carbons to which they are attached form an aromatic six-membered carbocyclic or N-heterocyclic ring and alkyl, alkoxy, dialkylamino or halogen derivatives thereof are active against Gram-positive and Gram-negative bacteria. They may be prepared by certain specified reactions of penicillins or 6-amino- penicillinic acid or functional derivatives thereof.

238194

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