C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/553 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2651226
The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.
La présente invention concerne des dérivés pentacycliques d'indole de formule (I) : où A, Ar, R1, R2, W, X, Y et Z sont tels que définis dans l'invention, ainsi que des sels de qualité pharmaceutique desdits dérivés, des compositions pharmaceutiques les incluant et leur application au traitement prophylactique ou thérapeutique d'une infection par le virus de l'hépatite C.
Capito Elena
Ferreira Maria Del Rosario Rico
Habermann Joerg
Narjes Frank
Stansfield Ian
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.p.a.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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